Best Nitric Oxide Supplements

Written by James Dixon

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Nitric Oxide supplements can do some serious wonders to your workout performance, your health, your wellbeing and even your cognitive function. We’ve been mining for the best nitric oxide supplements, with one overall winner. Find them all right here…

For many people these days – myself very much included – regular exercise is an integral part of life. Any supplement that can boost your workouts can therefore be very welcome.

This is where nitric oxide supplements come into play. Nitric oxide is responsible for increasing blood flow in your body, allowing essential nutrients to reach your muscles. A surge of nitric oxide can have a significant impact on your training, providing a boost in energy, increasing endurance, and promoting muscle growth.

Happily, there are plenty of supplements out there that can help to boost nitric oxide levels. However, there are perhaps too many – with such a plethora of options available, finding the best nitric oxide supplement can be a daunting task.

We’ve done our best, though. Below, we’ve got what we believe are the best of the best nitric oxide supplements available right now.

Transparent Labs Nitric Oxide bottle

Transparent Labs Nitric Oxide is undeniably the top choice for boosting nitric oxide levels.

With a potent formula, transparent labeling (pun not intended!), and a reputation for quality, it easily surpasses the competition in effectiveness and customer satisfaction.

I love it – it should help to supercharge your workouts whilst ably delivering the many other benefits that heightened nitric oxide levels have to offer.

Our top nitric oxide supplements

With all this in mind, NO supplementation looks like a promising avenue of approach for many people looking to live a healthier, more active life. There are plenty of supplements out there, of course. This list represents the cream of the crop – the best NO supplements going.

Transparent Labs Nitric Oxide

Transparent Labs Nitric Oxide bottle

Transparent Labs Nitric Oxide is a top-of-the-line supplement designed to boost the production of nitric oxide in the body.

One of the standout features of Transparent Labs Nitric Oxide is the exceptional quality of its ingredients. It is made using only premium ingredients that have undergone rigorous testing for purity and potency. Each ingredient is carefully sourced to ensure the highest quality standards are met.

The key ingredient found in Transparent Labs Nitric Oxide is L-citrulline. It’s an amino acid that has been scientifically studied and proven to boost nitric oxide production in the body.

By increasing nitric oxide levels, L-citrulline promotes the vasodilation we want to see – this relaxes and widens blood vessels, leading to improved blood flow to the muscles during exercise.

As we have seen, this enhanced blood flow is crucial for delivering oxygen and nutrients to the muscles, resulting in increased endurance, reduced fatigue, and improved muscle pumps.

Additionally, Transparent Labs Nitric Oxide makes great use of Betaine Anhydrous in its formula. Betaine Anhydrous has been recognized for its ability to enhance athletic performance and exercise capacity. It promotes cellular hydration, which is essential for optimal muscle function.

By maintaining proper hydration levels within the muscle cells, Betaine Anhydrous contributes to enhanced endurance and improved overall workout performance.

To further optimize its efficacy, Transparent Labs Nitric Oxide uses BioPerine®. BioPerine® is a patented black pepper extract that has been shown to increase the bioavailability and absorption of nutrients. With higher bioavailability, the body can better absorb and utilize the beneficial ingredients in Transparent Labs Nitric Oxide, ensuring that you can make the most of their potential benefits.

Transparent Labs Nitric Oxide offers incredibly precise and effective dosing. The supplement is made with optimal amounts of each ingredient, ensuring that users receive the right dosage for maximum benefits. This attention to detail sets Transparent Labs Nitric Oxide apart, as it eliminates the guesswork often associated with other supplements on the market.

As you should expect of such a top-tier supplement, Transparent Labs Nitric Oxide is entirely free from harmful additives or artificial preservatives. It is a natural and safe supplement, made with the utmost consideration for the health and well-being of its users.

Transparent Labs Nitric Oxide’s superior quality ingredients, effective dosing, and commitment to purity make it an exceptional supplement for enhancing nitric oxide levels. It’s one of the main NO supplements that I would personally plump for – in fact, it’s one that I often do.

The inclusion of scientifically validated ingredients like L-citrulline, Betaine Anhydrous, and BioPerine® ensures that you can experience the full benefits of increased nitric oxide production. Transparent Labs Nitric Oxide really is a keen ally if you’re looking to optimize your workouts and more ably achieve your fitness goals.

CrazyBulk Nitric Max

CrazyBulk Nitric Max bottle

I almost always like CrazyBulk products, so it’s great to see their entry into the NO world taking off so well.

And it’s no wonder – CrazyBulk Nitric Max is a powerful nitric oxide-boosting supplement that aims to provide seasoned athletes and more casual fitness enthusiasts alike with enhanced performance and improved muscle gains.

CrazyBulk Nitric Max boasts an impressive formula. Its recipe contains key ingredients such as L-arginine, L-citrulline, and Beta-Alanine, all of which are known for their ability to enhance nitric oxide levels in the body.

This potent combination helps to relax and widen blood vessels, resulting in increased blood flow and improved nutrient delivery to the muscles during workouts. This, in turn, can lead to enhanced exercise performance and greater endurance, allowing you to train harder, for longer.

Moreover, CrazyBulk Nitric Max is carefully dosed to ensure optimal efficacy. Each ingredient’s precise dosage is formulated to maximize the benefits on offer, promoting muscle pump, vascularity, and overall strength gains. By boosting nitric oxide levels, you should experience improved muscle recovery and reduced fatigue when using CrazyBulk Nitric Max, enabling you to push through intense workouts more efficiently.

CrazyBulk Nitric Max is made by Wolfson Brands, who own and operate the whole CrazyBulk line – alongside some of my all-time favorite supplements like NooCube and PhenQ. With a commitment to quality, innovation, and customer satisfaction, Wolfson Brands are leaders in the supplements industry.

Their dedication to using premium ingredients, rigorous testing, and advanced manufacturing techniques sets them apart from the competition. They are known for their exceptional customer service and transparency, providing full ingredient disclosure and educational resources. I really am a big fan.

CrazyBulk Nitric Max upholds this kind of standard. It is known for its quick results, which is unsurprising given its ingredients list. Many users report feeling an intense muscle pump shortly after taking the supplement, along with increased energy levels and improved focus. I’ve felt this myself and can happily say that it’s fantastic.

In summary, CrazyBulk Nitric Max is an impressive nitric oxide booster that can take your workout performance and muscle gains to the next level. If Transparent Labs Nitric Oxide didn’t exist then I would happily give Nitric Max the top spot. Even then, I’m a little torn.

The carefully selected ingredients, precise dosing, and commitment to quality and safety make it a perfect choice for anybody looking to benefit from increased NO levels.

VigRX Nitric Oxide Support

VigRX NO Support bottle

VigRX Nitric Oxide Support is made in the same kind of mold – it’s a high-quality supplement designed to boost NO levels in the body, boasting an impressive formula in line with other offerings on this list.

VigRX contains a scientifically optimized blend of well-known nitric oxide boosting ingredients including the likes of L-arginine, L-citrulline, and Beetroot extract. These ingredients work together to support the body’s natural nitric oxide-producing capacity, doing everything you would expect of a top-shelf NO supplement.

L-arginine is a vital amino acid that serves as a precursor to nitric oxide synthesis. It enhances nitric oxide production, leading to increased blood flow, improved oxygen delivery, and enhanced exercise performance.

L-citrulline complements L-arginine by stimulating nitric oxide production and promoting vasodilation, resulting in improved blood flow and muscle pump.

Beetroot extract, rich in nitrates, further supports nitric oxide production and vasodilation, enhancing endurance and workout capacity. These ingredients are pretty inspired, working synergistically to each make the most of one another.

And, as you might expect, VigRX Nitric Oxide Support is formulated with optimal doses of each ingredient, ensuring that users receive a precise and effective dosage that will yield maximum benefits. This optimized dosage also helps to reduce the risk of potential side effects, making it a safe and natural supplement that athletes and fitness enthusiasts can use with confidence.

It is incredibly high-quality, manufactured in a cGMP-certified facility, ensuring the highest level of quality control in every batch. Additionally, all the ingredients used in the formulation of VigRX Nitric Oxide Support are sourced from reputable suppliers and undergo rigorous testing to ensure purity, safety, and effectiveness.

WooHoo Natural Nitric Oxide

WooHoo Natural Nitric Oxide bottle

Finally, WooHoo Natural Nitric Oxide gives us what we have come to expect of this list – again, it’s a potent NO booster whose cleverly formed ingredients list should work wonders in giving you all the benefits you should expect of increased nitric oxide levels.

With 120mg of Vitamin C, it provides 200% of the recommended daily value, which plays a crucial role in nitric oxide synthesis. Vitamin C acts as a cofactor for the enzyme responsible for converting L-arginine into nitric oxide, enhancing its effectiveness as a precursor.

Then there is plenty of Vitamin E, which acts as an antioxidant, protecting nitric oxide from degradation and prolonging its effects in the body.

You also get 200% of your recommended daily intake of folic acid, with 0.8mg. This should ably assist in nitric oxide production – it helps in converting L-arginine to nitric oxide, facilitating a more efficient pathway for nitric oxide synthesis.

Which leads us onto the heart of the formula –WooHoo Natural delivers a potent dosage of L-arginine. L-arginine serves as a direct precursor for nitric oxide synthesis, supporting improved blood flow, vasodilation, and enhanced exercise performance.

L-Citrulline complements this L-arginine by promoting nitric oxide production and vasodilation. It works synergistically with L-arginine to extend nitric oxide effects, resulting in improved muscle pumps, increased endurance, and reduced fatigue during workouts.

Finally, you get a good kick of alpha-lipoic acid, which further enhances WooHoo Natural’s efficacy as a nitric oxide booster. It increases nitric oxide bioavailability and optimizes its utilization in the body, maximizing the benefits of the other ingredients.

Each serving of WooHoo Natural Nitric Oxide provides optimal dosages of these key ingredients, ensuring that you receive optimal benefits. The supplement is formulated with precision, taking into account the appropriate ratios and concentrations required for optimal nitric oxide support. This attention to detail ensures that you get the most out of each dose and experience noticeable results.

WooHoo Natural Nitric Oxide is fantastic. It’s one of my favorites, and not simply for its name (top marks there, of course). It’s a high-quality supplement that can significantly enhance athletic performance. With its natural ingredients, optimal dosages, and a whole lot of strong positive feedback from users, it represents a reliable choice for anybody looking to optimize their workouts and achieve greater fitness gains.


Transparent Labs Nitric Oxide bottle

It’s a tough call. These supplements all do much the same thing in much the same way. They all share the same basic DNA, albeit with a few tweaks and subtle differences here and there.

So it’s down to these tweaks and subtle differences, in the end – they will help to separate the wheat from the chaff. Or, rather, the wheat from the slightly (slightly!) less good wheat.

This leads us to Transparent Labs Nitric Oxide, something of a premier choice for anybody looking to boost their nitric oxide levels.

Boasting an incredibly good, reliable formulation, transparent labeling practices, and an unwavering commitment to quality, this supplement surpasses its competition by a whisker.

Transparent Labs Nitric Oxide sets itself apart through its superior selection of premium and scientifically validated ingredients. The supplement harnesses the potency of L-citrulline, Bioperine®, and an array of other compounds with proven efficacy in boosting nitric oxide production. This well-curated blend facilitates enhanced blood flow, amplified muscle pumps, and heightened performance during workouts.

Moreover, Transparent Labs Nitric Oxide distinguishes itself through its meticulous approach to manufacturing. Made in a cutting-edge FDA-registered facility, this supplement adheres to the most exacting quality standards. As a result, each bottle contains a meticulously crafted formula that is free from impurities, ensuring a safe and efficacious product.

The efficacy of Transparent Labs Nitric Oxide is consistently lauded by users. I happily laud it myself. Heightened energy levels and increased endurance to pronounced muscle pumps… it’s all yours for the taking, if you want it.

Transparent Labs Nitric Oxide’s ability to augment blood flow and facilitate nutrient delivery to muscles is indispensable in promoting stamina and mitigating fatigue, resulting in remarkably productive training sessions.

To build on this, Transparent Labs has fostered a sterling reputation for customer satisfaction. This isn’t unique by any stretch of the imagination. However, it’s something you can’t take for granted in today’s often uncaring supplement market, and it’s something I definitely always like to see and flag up.

The company boasts an exceptional level of customer service, promptly addressing customer inquiries and providing invaluable support. Their steadfast commitment to customer satisfaction is further reinforced by their comprehensive 100% money-back guarantee, which means that you can buy into them with a good degree of peace of mind.

Transparent Labs are a shade ahead in an incredibly strong market – Transparent Labs Nitric Oxide tops an incredibly strong list (though, admittedly, only just!).

What is nitric oxide?

There is nothing too fancy about nitric oxide (NO). Simply, it’s a gas, a chemical compound that is naturally produced in the body.

Nitric Oxide is a signaling molecule produced by the endothelial cells, which line the inner surface of blood vessels and are responsible for regulating blood flow by controlling the dilation of blood vessels. It is involved in various physiological processes, including vasodilation, neurotransmission, and immune system responses.

NO plays an important role in regulating blood pressure, improving circulation, and reducing inflammation. It is also used medically to treat certain conditions, such as pulmonary hypertension and erectile dysfunction.

How can nitric oxide supplementation help you?

The amount of NO present in the body can be increased by making good use of nitric oxide supplements. Given its various roles in the process mentioned above, it’s no surprise that NO supplementation can give you some really quite profound health and fitness benefits.

Improved exercise performance

Nitric oxide supplements have gained popularity in large part for their ability to boost athleticism and athletic ability. By taking nitric oxide supplements, you can experience improved blood flow and optimized oxygen delivery to your muscles.

This in turn leads to better aerobic and anaerobic performance, allowing you to train harder and for longer, all whilst recovering faster.

During exercise, the demand for oxygen and nutrients from working muscles increases. As we have seen, NO helps to dilate blood vessels, enabling enhanced blood flow to the muscles.

This increased blood flow delivers a greater supply of oxygen and nutrients, which are essential for optimal muscular function and energy production. As a result, you may experience improved endurance, reduced fatigue, and increased exercise capacity.

A study published in the International Journal of Sports Nutrition and Exercise Metabolism examined the effects of nitric oxide supplements on exercise performance. The study involved athletes who were randomly assigned to either a nitric oxide supplement group or a placebo group. The researchers found that athletes who took nitric oxide supplements were able to exercise for a longer duration with less perceived fatigue compared to those in the placebo group.

Furthermore, nitric oxide supplements may aid in preventing exercise-induced fatigue, including symptoms of delayed onset of muscular soreness (or DOMS, to you and me).

Fatigue during and after intense physical activity can limit performance and hinder progress towards fitness goals. It can make life pretty miserable in the days after a hard workout, as muscles ache and energy levels are low. Nitric oxide helps to regulate and optimize the oxygen and energy supply to muscles, reducing fatigue and enhancing endurance.

It is important to note that nitric oxide supplements are not a magic solution for achieving athletic prowess. They should be used in conjunction with a well-rounded exercise program, proper nutrition, hydration, and, especially, adequate rest.

However, a good supplement routine plays a large role here, a routine to which a good NO booster like those in our list below may represent a great addition.

Lower blood pressure

Nitric oxide supplements have been found to have the potential to lower blood pressure, which is a significant benefit for individuals with hypertension or high blood pressure. This is unsurprising, really, when you consider its role in facilitating vasodilation.

High blood pressure is a common health condition that increases the risk of developing cardiovascular diseases such as heart disease and stroke.

In fact, it’s currently one of the world’s biggest killers.

The mechanism by which nitric oxide supplements can help lower blood pressure is through their ability to improve blood circulation and widen blood vessels, as we have seen – this is vasodilation.

Nitric Oxide is a powerful vasodilator. It plays a crucial role in regulating blood vessel tone.

By promoting vasodilation, nitric oxide supplements allow for better blood flow and decreased resistance, which can ultimately reduce blood pressure.

A review published in the Cochrane Library examined the effects of nitric oxide supplements on blood pressure in individuals with hypertension. The review analyzed several randomized controlled trials that investigated the impact of nitric oxide supplements on blood pressure levels. The findings of the review indicated that the consumption of nitric oxide supplements significantly lowered blood pressure levels in people with hypertension.

Improved erectile function

Nitric oxide supplements have demonstrated potential in improving erectile function, particularly in men with erectile dysfunction (ED). Erectile dysfunction is a condition characterized by the inability to achieve or maintain an erection sufficient for sexual activity.

Nitric oxide plays a crucial role in the process of achieving and maintaining an erection. It functions as a signaling molecule that triggers the relaxation of smooth muscle cells in the penis’ blood vessels, leading to increased vasodilation and, hence, blood flow.

This increased blood flow is essential for the penis to become erect. Insufficient production of nitric oxide can hinder this process and contribute to erectile dysfunction.

Nitric oxide supplements aim to enhance the production of nitric oxide in the body, which in turn should improve blood flow to the penis and potentially enhance erectile function. By boosting the levels of nitric oxide, these supplements support the dilation of blood vessels and optimize blood flow to the erectile tissues, promoting stronger and longer-lasting erections.

A review published in the Journal of Sexual Medicine examined the effects of nitric oxide supplements on erectile function in men with erectile dysfunction. The review analyzed several clinical trials and found that nitric oxide supplements significantly improved erectile function in the study participants.

NO supplementation isn’t a cure. It won’t deal with the mental or physical concerns underpinning ED. However, it goes a long way as part of a broader treatment plan, and represents a nice added bonus for any athlete using a good NO supplement.

Better sleep quality

Nitric oxide supplements have shown potential in improving sleep quality, particularly in those suffering from insomnia. For me, this, more than vasodilation in itself, is what makes NO supplementation so key for athleticism.

Nitric oxide plays a role in regulating blood flow to the brain and promoting relaxation of blood vessels, which can contribute to better sleep – blood flow to the brain is essential for adequate oxygen and nutrient supply, as well as for the removal of waste products.

This enhanced blood flow can support optimal brain function and promote better sleep quality.

In a study published in the journal Sleep, researchers investigated the effects of nitric oxide supplements on sleep quality in elderly adults with insomnia. The study involved a randomized, double-blind, placebo-controlled trial where participants were either given nitric oxide supplements or a placebo for a certain duration.

The findings revealed that the group receiving nitric oxide supplements experienced significant improvements in sleep quality compared to the placebo group. These improvements included reduced time to fall asleep, enhanced sleep duration, and improved overall sleep satisfaction.

Improved cognitive function

This increased blood flow to the brain should also give cognitive benefits, as you might expect. And, indeed, NO supplements have shown promise in improving cognitive function, including memory, focus, and mental clarity.

Optimal blood flow to the brain is critical for its proper functioning, as it ensures the delivery of oxygen and nutrients necessary for neural activity. Nitric oxide plays a role in regulating blood vessel tone and promoting vasodilation, which leads to increased blood flow to the brain.

This improved blood flow can enhance cognitive function by providing the brain with everything it needs to perform more optimally.

A study published in the journal Frontiers in Aging Neuroscience investigated the effects of nitric oxide supplements on cognitive function in elderly adults. Again, the study involved a randomized, double-blind, placebo-controlled trial during which participants were given either NO supplements or a placebo for a specified period.

The results showed that the group receiving nitric oxide supplements exhibited improved cognitive performance compared to the placebo group. This improvement was observed in various cognitive domains, including memory, attention, and overall cognitive function.

Enhanced immune function

Finally, nitric oxide supplements have been found to possess immune-enhancing properties, which can help to bolster the body’s defense against infections and viruses. A strong immune system is vital for overall health and protection against pathogens.

Nitric oxide plays a crucial role in immune function and acts as a signaling molecule that regulates various immune responses. It helps to stimulate the immune system by promoting the activity of immune cells, such as macrophages and natural killer cells, which are responsible for identifying and eliminating infectious agents.

A study published in the Journal of the International Society of Sports Nutrition explored the effects of nitric oxide supplements on immune function in athletes. The study involved administering nitric oxide supplements to a group of athletes and measuring various immune parameters.

The researchers found that nitric oxide supplementation significantly increased immune function in the athletes, as evidenced by enhanced immune cell activity and improved immune response.

However, it is worth noting that more research is needed to further understand the specific mechanisms by which nitric oxide supplements enhance immune function and how these effects may vary in different populations.